The Allen Lab has published over 65 research articles that utilize X-ray crystallography, with more than 145 protein structures deposited in the Protein Data Bank
Click here for a complete list of the lab's published work
Click here for a complete list of structures determined in the lab and deposited in the PDB
Recapitulating the Binding Affinity of Nrf2 for KEAP1 in a Cyclic Heptapeptide, Guided by NMR, X-ray Crystallography, and Machine Learning. Ortet PC, Muellers SN, Viarengo-Baker LA, Streu K, Szymczyna BR, Beeler AB, Allen KN, Whitty A. J Am Chem Soc. 2021 Mar 17;143(10):3779-3793. doi: 10.1021/jacs.0c09799. Epub 2021 Mar 8. PMID: 33683866.
Fast Kinetics Reveals Rate-Limiting Oxidation and the Role of the Aromatic Cage in the Mechanism of the Nicotine-Degrading Enzyme NicA2. Tararina MA, Dam KK, Dhingra M, Janda KD, Palfey BA, Allen KN. Biochemistry. 2021 Feb 2;60(4):259-273. doi: 10.1021/acs.biochem.0c00855. Epub 2021 Jan 19. PMID: 33464876.
Glycoconjugate pathway connections revealed by sequence similarity network analysis of the monotopic phosphoglycosyl transferases. O'Toole KH, Imperiali B, Allen KN. Proc Natl Acad Sci U S A. 2021 Jan 26;118(4):e2018289118. doi: 10.1073/pnas.2018289118. PMID: 33472976; PMCID: PMC7848588.
Catch and Anchor Approach To Combat Both Toxicity and Longevity of Botulinum Toxin A. Lin L, Olson ME, Sugane T, Turner LD, Tararina MA, Nielsen AL, Kurbanov EK, Pellett S, Johnson EA, Cohen SM, Allen KN, Janda KD. J Med Chem. 2020 Oct 8;63(19):11100-11120. doi: 10.1021/acs.jmedchem.0c01006. Epub 2020 Sep 18. PMID: 32886509; PMCID: PMC7581224.
Bioinformatic Analysis of the Flavin-Dependent Amine Oxidase Superfamily: Adaptations for Substrate Specificity and Catalytic Diversity. Tararina MA, Allen KN. J Mol Biol. 2020 May 1;432(10):3269-3288. doi: 10.1016/j.jmb.2020.03.007. Epub 2020 Mar 19. PubMed PMID: 32198115; PubMed Central PMCID: PMC7321841.
Lanthanide-Binding Tags for 3D X-ray Imaging of Proteins in Cells at Nanoscale Resolution. Victor TW, O'Toole KH, Easthon LM, Ge M, Smith RJ, Huang X, Yan H, Chu YS, Chen S, Gursoy D, Ralle M, Imperiali B, Allen KN, Miller LM. J Am Chem Soc. 2020 Feb 5;142(5):2145-2149. doi: 10.1021/jacs.9b11571. Epub 2020 Jan 21. PubMed PMID: 31923358.
Structural Basis of the Molecular Switch between Phosphatase and Mutase Functions of Human Phosphomannomutase 1 under Ischemic Conditions. Ji T, Zhang C, Zheng L, Dunaway-Mariano D, Allen KN. Biochemistry. 2018 Jun 26;57(25):3480-3492. doi: 10.1021/acs.biochem.8b00223. Epub 2018 May 11. PubMed PMID: 29695157.
Membrane association of monotopic phosphoglycosyl transferase underpins function. Ray LC, Das D, Entova S, Lukose V, Lynch AJ, Imperiali B, Allen KN. Nat Chem Biol. 2018 Jun;14(6):538-541. doi: 10.1038/s41589-018-0054-z. Epub 2018 May 16. PubMed PMID: 29769739; PubMed Central PMCID: PMC6202225.
Exploring the structural origins of cryptic sites on proteins. Beglov D, Hall DR, Wakefield AE, Luo L, Allen KN, Kozakov D, Whitty A, Vajda S. Proc Natl Acad Sci U S A. 2018 Apr 10;115(15):E3416-E3425. doi: 10.1073/pnas.1711490115. Epub 2018 Mar 26. PubMed PMID: 29581267; PubMed Central PMCID: PMC5899430.
