Karen N. Allen

Karen received her B.S. degree in Biology, cum laude from Tufts University and her Ph.D. in Biochemistry from Brandeis University, where she was a Dretzin scholar. Her graduate studies in the laboratory of the mechanistic enzymologist, Dr. Robert H. Abeles, focused on the design, synthesis, and inhibition kinetics of transition-state analogues of esterases. Following her desire to see enzymes in action she pursued X-ray crystallography during postdoctoral studies as an American Cancer Society Fellow in the laboratory of Drs. Gregory A. Petsko and Dagmar Ringe. Since 1993, she has lead her own research team at Boston University, first in the Department of Physiology and Biophysics at the School of Medicine, and since 2008 in the Department of Chemistry where she is now a Professor. She lives in Weston, MA with her husband and an energetic dog. Dr. Allen's research has focused on the elucidation of enzyme mechanisms and the understanding of how Nature has evolved new chemistries from existing protein scaffolds. Within this context, her laboratory has plumbed the basis of enzyme-mediated phosphoryl and phosphoglycosyl transfer and decarboxylation reactions. She is Associate Editor of the Beilstein Journal of Organic Chemistry, counselor for the Northeastern Section of the American Chemical Society, and is an ASBMB fellow.

Postdoctoral Fellows
Undergraduate Students
Graduate Students

Jim Conley

6th Year Pharmacology

Ashley Rebelo

6th Year Chemistry

Former Lab Members

Jac Lorenzo

5th Year Pharmacology

Dr. Muazza Shahid

Dr. Anthony DeMaria (CAS Chemistry '23) - MIT: Postdoctoral Fellow

Tina Chen (CAS Biochemistry & Molecular Biology '23)

Dr. Samantha Muellers - Gingko Bioworks: Protein Engineer III

Benjamin Pollak (CAS Chemistry '22) - UC San Diego: PhD in Biochemistry and Biophysics

Gwendolyn Pyeatt (CAS Biochemistry & Molecular Biology '21) - University of Cambridge: PhD program in Biochemistry

Jack Jordanides (ENG Biomedical Engineering '21) - The Wyss Institute: Research Assistant

Dr. Jozlyn Clasman - Agios Pharmaceuticals: Structural Biologist

Dr. Katherine O'Toole - New England Biolabs: Postdoctoral Fellow

Dr. Margarita Tararina - University of Pennsylvania: Postdoctoral Fellow

Manaswni Dhingra (CAS Chemistry '20) - Civetta Therapeutics: Research Associate

Sonika Vatsa (CAS Biochemistry & Molecular Biology '19) - Massachusetts General Hospital Cancer Center: Research Technician 

Katie Dam (CAS Biochemistry & Molecular Biology '18)  -Boston University School of Medicine: MD Candidate

Grace Ferri  (CAS Biochemistry & Molecular Biology '18) - Boston University School of Medicine: MD Candidate

Dr. Christine Harvey - Civetta Therapeutics: Scientist 1 

Merissa Brousseau (CAS Biochemistry & Molecular Biology '18) - University of Wisconsin - Madison: PhD candidate

Dr. Leah Ray - Pfizer: Manager, Medical Writing 

Kelly Huynh (CAS Biochemistry & Molecular Biology '15) - Duke University: PhD candidate

Dr. Steve Cohen (CAS Biochemistry & Molecular Biology '15) - Biogen: Postdoctoral Fellow

Olivia Hallett-Ebeling (CAS Biochemistry & Molecular Biology '14) 

Dr. Justin Marinko (CAS Chemistry: Biochemistry '14) - Stanford University: Postdoctoral Fellow

Dr. Jeremiah Farelli - Omega Therapeutics: Associate Director

Dr. Chetanya Pandya - bluebird bio: Senior Data Scientist

Eddie Willis (Roxbury Community College Intern 2013) - Advanced Instruments, Inc: Nurse

Lisa Kellndorfer (CAS Biochemistry & Molecular Biology '13) - Austin Street Brewery: Production Manger

Miyuki Aono (CAS Biochemistry & Molecular Biology '13) - Takeda: Product Manager / Oncology

Megan Garland  (CAS Chemistry: Biochemistry and Neuroscience '12) - Stanford University: MD/PhD program

Juan Ramirez (SURF student 2011) - Accenture: Technology Analyst

Dr. Robert MacDonald (CAS Biochemistry & Molecular Biology '11) - Cell Signaling Technology: Scientist

Dr. Nikhil Shah (CAS Biochemistry & Molecular Biology '11) - University of Florida: General Cardiology Fellow

Dr. John Facendola (CAS Chemistry '11) - Intel Corporation: Process Development Engineer

Dr. Kelly D.D. Broccio - Oerth Bio: Senior Director, Biology

Ashish Sarraju (CAS Chemistry: Biochemistry '09) - Northwestern University: Feinberg School of Medicine

Dr. Nicholas Silvaggi - University of Wisconsin, Milwaukee: Associate Professor

Dr. Meng-Chiao Ho - Academia Sinica, Taiwan: Associate Professor

Dr. Sushmita Lahiri - Boehringer Ingelheim: Director of External Innovation, Research Beyond Borders

Dr. Kay Choi - University of Texas Medical Branch at Galveston: Associate Professor

Dr. Cornelia Bellamacina - Crystallographic Consulting, LLC: Contract Scientist

Dr. Marc Morais - University of Texas Medical Branch at Galveston: Associate Professor

Rebecca Koweek

2nd Year Chemistry

Dr. Neno Vuksanovic

Ph.D. in Chemistry '20 University of Wisconsin-Milwaukee 

Vibhuti Amin

CAS Chemistry '24

Kristin Hughes

4th Year Chemistry

Dr. Hayley Knox

Ph.D. in Chemistry '21 Pennsylvania State University

Takumi Hawes

3rd Year Chemistry

Roxanne Siuda

3rd Year Pharmacology

Hannah Braverman

1st Year Chemistry

Kat Nguyen

1st Year Chemistry

Amanda Newell

1st Year Pharmacology

Martin Dokholyan

CAS Biochemistry and Molecular Biology '26

Nikhil Khemani

CAS Chemistry '27